Rapidly obtain sections as skinny or thick as your software necessitates, with out worrying about shedding or distorting important tissue samples.
Our transform-key SmartBatch+ method combines electrophoretic tissue clearing and immunolabeling into a single large-throughput unit.
Antibodies might consider weeks to diffuse through only a few millimeters of tissue, with a steep labeling gradient from surface to core.
Megatome is designed for precision: the blade vibrates at a higher frequency and bigger amplitude vary than other microtomes, and encompasses a one of a kind deflection Command system.
SE takes advantage of a rotational electric powered field to disperse highly electromobile molecules (which include antibodies or surfactant micelles) all over a porous sample devoid of detrimental electrically charged structures within the tissue. This allows two-4 day clearing of intact organs,
Our preformulated EasyIndex Resolution raises and homogenize the refractive index of delipidated tissue samples, rendering them totally transparent. This allows gentle penetration in to the sample and ensures the acquisition of superior-resolution, in-concentration impression information.
Megatome is often a novel microtome that permits for top-precision sectioning of a wide array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with small tissue injury megatomi.com and information reduction.
It’s the perfect time to improve your microtome to Megatome. With exact large-frequency slicing for an unmatched range of sample measurements and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for various applications.
Absolutely delipidate complete mouse brains or comparably sized samples in only one day with SmartBatch+, or in a single week with our passive clearing package.
Docset creation calls for at minimum two possibilities: the name on the docset and The situation in the Javadoc data files to include from the docset.
This tends to produce a docset named Sample in The present Listing. Docset creation is often customized with optional arguments:
Protect avoids the variability of hydrogel embedding and the information loss from PFA preservation, shielding specimens for various rounds of processing.
--displayName: Will established the identify as shown in Dash. This is certainly helpful in the event you produce a docset with identify SampleProject but Screen identify Sample Project as an alternative. This placing will default to the worth of --identify if omitted.
Our novel Defend tissue preservation strategy sorts intramolecular bonds using polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.